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Functional validation of LINC00511 and SNHG15 in activation of cardiac fibroblasts. (A) Knockdown of expression of LINC00511 and SNHG15 reduced expression of myofibroblast-associated genes. (B) Depletion of LINC00511 and SNHG15 can reduce collagen secretion in HCF-cultured supernatants. (C) Depletion of LINC00511 and SNHG15 can reduce myofibroblast proliferation in 1 and 2 days, respectively. n = 3 per group. *P < 0.05, **P < 0.01, ***P < 0.001.
