Table 4.
Genes down-regulated (> 1.5-fold change) in the mutant strain.
| Cluster | Gene | logFC | pvalue | function |
|---|---|---|---|---|
| 1 | VPA1504 | -2.15582 | 1.68E-11 | Sigma-fimbriae tip adhesin |
| VPA1505 | -1.83097 | 3.17E-10 | Sigma-fimbriae usher protein | |
| VPA1506 | -1.85957 | 5.85E-10 | Sigma-fimbriae usher protein | |
| VPA1507 | -1.80196 | 6.91E-10 | Sigma-fimbriae usher protein | |
| VPA1508 | -1.66659 | 2.43E-09 | Sigma-fimbriae usher protein | |
| VPA1509 | -1.76698 | 1.29E-09 | Sigma-fimbriae chaperone protein | |
| 2 | VPA0636 | -1.55671 | 1.22E-07 | Arginine ABC transporter |
| VPA0637 | -1.69805 | 1.73E-09 | Arginine ABC transporter | |
| VPA0638 | -1.5677 | 3.61E-08 | Arginine ABC transporter | |
| 3 | VPA1099 | -1.95092 | 7.45E-08 | Predicted redox protein |
| VPA1100 | -2.42168 | 1.19E-14 | Sensor histidine kinase | |
| VPA1101 | -2.11042 | 2.77E-12 | Cytochrome c551 peroxidase | |
| 4 | VP2423 | -4.58784 | 2.59E-33 | hypothetical protein |
| VP2424 | -4.46142 | 4.30E-42 | Type IV prepilin peptidase TadV/CpaA | |
| VP2425 | -4.65177 | 3.56E-42 | Type IV prepilin peptidase TadV/CpaA | |
| VP2426 | -3.03105 | 1.31E-25 | Predicted ATPase with chaperone activity | |
| VP2427 | -3.02567 | 1.85E-24 | Flp pilus assembly protein RcpC/CpaB | |
| VP2428 | -2.55322 | 7.99E-19 | Type II/IV secretion system secretin RcpA | |
| VP2429 | -1.75485 | 0.000238 | hypothetical protein | |
| VP2430 | -1.97074 | 2.91E-12 | Von Willebrand factor type A domain protein | |
| VP2431 | -1.86147 | 6.08E-11 | Similar to TadZ/CpaE | |
| VP2432 | -1.78401 | 5.98E-10 | Similar to TadZ/CpaE | |
| VP2433 | -1.76889 | 2.37E-10 | Type II/IV secretion system ATPase TadZ/CpaE | |
| VP2434 | -1.73857 | 5.29E-10 | Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF | |
| VP2435 | -1.80475 | 2.63E-10 | Flp pilus assembly protein TadB | |
| VP2436 | -1.74251 | 1.77E-09 | Type II/IV secretion system protein TadC | |
| VP2437 | -1.7222 | 9.38E-10 | TPR repeat protein | |
| 5 | VP2261 | -3.03897 | 1.46E-21 | Flagellin protein FlaF |
| VP2262 | -3.36217 | 2.86E-28 | Flagellin protein FlaD | |
| VP2263 | -3.51179 | 1.21E-32 | Flagellin protein FlaA | |
| VP2264 | -3.24318 | 1.29E-28 | Flagellar protein FlaG | |
| VP2265 | -3.29545 | 2.24E-29 | Flagellar cap protein FliD | |
| VP2266 | -3.3816 | 2.61E-19 | Polar flagellar rod protein FlaI | |
| VP2267 | -2.97178 | 1.54E-22 | Flagellar biosynthesis protein FliS | |
| 6 | VP1657 | -1.99881 | 3.80E-12 | Type III secretion host injection protein (YopB) |
| VP1658 | -2.12616 | 3.16E-13 | Type III secretion negative regulator protein (YopD) | |
| 7 | VP1476 | -2.68838 | 9.64E-13 | Anti-sigma regulatory factor SypA |
| VP1477 | -1.58128 | 1.64E-07 | Outer membrane protein SypB | |
| VP1478 | -1.53419 | 1.10E-06 | Predicted protein SypD | |
| VP1479 | -1.6465 | 8.60E-05 | Signal transduction histidine kinase SypF | |
| VP1480 | -1.75662 | 7.30E-08 | Oligosaccharide translocase SypK | |
| VP1481 | -1.72636 | 5.83E-07 | Membrane protein SypL | |
| VP1482 | -2.82179 | 3.63E-14 | Glycosyltransferase SypN | |
| VP1483 | -3.18243 | 2.64E-15 | SypO | |
| VP1484 | -1.66319 | 4.82E-06 | Glycosyltransferase SypQ | |
| VP1485 | -3.20651 | 8.60E-05 | Sugar transferase SypR | |
| VPA1403 | -2.2481 | 0.000113 | Capsular polysaccharide synthesis enzyme CpsA | |
| VPA1406 | -1.54633 | 9.98E-06 | Capsular polysaccharide synthesis enzyme CpsD | |
| 8 | VP0791 | -2.52929 | 5.65E-11 | Flagellin protein FlaE |
| VP0792 | -3.17949 | 3.71E-24 | Flagellin protein FlaD | |
| VP0793 | -2.61879 | 1.70E-19 | Flagellin protein FlaC | |
| VP0794 | -2.43402 | 5.55E-16 | Flagellar hook-associated protein FlgL | |
| VP0795 | -2.2913 | 1.66E-14 | Flagellar hook-associated protein FlgK | |
| VP0796 | -2.39126 | 1.93E-13 | Flagellar protein FlgJ [peptidoglycan hydrolase] | |
| VP0797 | -2.70585 | 7.15E-18 | Flagellar P-ring protein FlgI | |
| VP0798 | -2.1387 | 7.01E-11 | Flagellar L-ring protein FlgH | |
| VP0799 | -2.49074 | 2.69E-16 | Flagellar basal-body rod protein FlgG | |
| VP0800 | -2.39727 | 4.95E-14 | Flagellar basal-body rod protein FlgF | |
| VP0801 | -1.86615 | 2.83E-11 | Flagellar hook protein FlgE | |
| VP0802 | -1.86572 | 3.50E-11 | Flagellar basal-body rod protein FlgD | |
| VP0803 | -1.88728 | 2.29E-11 | Flagellar basal-body rod protein FlgC | |
| VP0804 | -1.92001 | 8.89E-12 | Flagellar basal-body rod protein FlgB | |
| VP0805 | -3.55641 | 1.93E-07 | Flagellar protein FlgP | |
| VP0806 | -2.28843 | 9.85E-15 | Flagellar protein FlgO |