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. 2021 Jan 21;7:588991. doi: 10.3389/fmed.2020.588991

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Copyright © 2021 Zhang, Bai, Zhang, Zheng, Lu, Liang, Lin and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clinical information of this adRP family. (A) Right eye fundus of the proband (III:1) presents characteristic RP degeneration, including a waxy pallor of optic disc, attenuated artery and vein and peripheral pigment deposit. (B) OCT scan reveals macular degeneration showing reduced thickness of outer nuclear layer (ONL) and RPE at the macular area with partial loss of outer/inner segments (OS/IS). (C,D) Fundus picture and Optical coherence tomography (OCT) scans of the left eye of the unaffected member (III:3) showing as normal controls. (E) Visual fields of the right eye of the proband indicates the tubular visual field.