Figure 4.

Graphed results for secondary analyses (only subjects who scored below norm at entry, on a specific test), primary outcome/cognitive measures for five NP tests and one domain score. These reflect the same factors as the primary analyses [time (pre-Tx entry, 1-Wk post- Tx, 1-Mo post- Tx); and treatment (sham, real), and their interaction], for each. The domain score for learning and memory reflects a composite score for seven NP tests: the CVLT (total; short and long delay - free and cued recall); and the rey-osterreith complex figure test (immediate and delayed recall). There was a consistent pattern across all graphs, where both groups showed improvement at 1 week post- the final, sham or real LED treatment, but only those who received real LED continued to improve at the 1-month, post- testing time point. Those who received sham, regressed at 1 month, approaching entry values.