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. 2021 Jan 21;11:574386. doi: 10.3389/fneur.2020.574386

Table 3.

Real LED equipment parameters and treatment specifications.

PhotoMedex LED lined helmet.
Each cluster head
MedX health LED cluster heads, 1 on each ear.
Each cluster head
Vielight red, 633 nm intranasal LED device Vielight NIR, 810 nm intranasal LED device Thor photomedicine LED lined helmet** Midline clusters turned on, only
Set A
Thor photomedicine
LED lined helmet**
left and right sides turned on, same time
Set B
Cluster head size 4.5 cm ×4.8 cm
(21.6 cm2)
2 inch diameter
(22.48 cm2)
1 cm2 1 cm2 6.3 cm diameter
(28.3 cm2)
6.3 cm diameter
(28.3 cm2)
Number of cluster heads 18 2 Single diode Single diode 5 10
No. of diodes per cluster head 20 52 1 1 69 69
Wavelength, nm 830 870 633 810 34–660; 35–850 34–660; 35–850
Power output, mW per cluster head 626 90 8 14.2 1,265.6 1,075.4
Power density, mW/cm2 29 4 8 14.2 41 35
Pulse frequency, Hz CW CW CW 10 CW CW
Pulse duty cycle, % 50
Total time per session 28 min 10 s* 4 min 25 min 25 min 10 min 42 s 12 min
36 s***
Dose: energy density, J/cm2 26 1 12 10.65 26 26
Joules 1,058 21.6 12 10.65 812.5 813
Total joules per device 19,043 43.2 12 10.65 4,063 8,130
*

Includes two sequential placement sets with nominal power output per cluster head, 626 mW: First placement set, midline only, 6 cluster heads turned on (14 min, 5 sec); Second placement set, Left and Right sides of head simultaneously, total 12 LED cluster heads turned on (14 min, 5 s). When PhotoMedex helmet, and two LED cluster heads over the ears, and two intranasals were used, Joules per treatment = 19.1 kJ, Total Joules after 15 Treatments = 286.6 kJ.

**

Used with participants where the head circumference was >24 inches.

***

Two sequential Placement Sets: Total Time, Set A plus Set B, was 23 min 18 sec. Note, the power output and power density varied slightly, for the different number of cluster heads turned on at the same time, 5 (Set A), or 10 (Set B). When Thor helmet, and two intranasals were used, Joules per Treatment = 12.2 kJ, Total Joules after 15 Treatments = 183.2 kJ.

CW, Continuous Wave.