Table 3. Analysis according to Preoperative Risk.
| High-risk induction (n=41) | High-risk non-induction (n=63) | p value | Low-risk (n=132) | |
|---|---|---|---|---|
| Baseline creatinine levels (mg/dL) | 0.53±0.20 | 0.58±0.26 | 0.293 | 0.67±0.19 |
| Time on waiting list (days) | 121.0 [29.0;244.0] | 26.0 [11.5;97.0] | 0.001 | 96.0 [46.0;189.5] |
| Pretransplantational admission | 39 (95.1) | 63 (100.0) | 0.153 | 30 (22.7) |
| Pretransplantational admission duration (days) | 32.0 [23.0;72.0] | 23.0 [13.0;37.0] | 0.003 | 0.0 [0.0;0.0] |
| Pretransplantational ICU care | 37 (90.2) | 59 (93.7) | 0.709 | 7 (5.3) |
| Pretransplantational ICU care duration (days) | 16.0 [11.0;28.0] | 14.0 [8.0;21.0] | 0.109 | 0.0 [0.0;0.0] |
| Pretransplantational ECMO support | 36 (87.8) | 39 (61.9) | 0.008 | 0 (0.0) |
| Pretransplantational ECMO support duration (days) | 12.0 [6.0;22.0] | 6.0 [0.0;14.5] | 0.003 | 0.0 [0.0;0.0] |
| Total operative time (hours) | 6.0[5.5;7.0] | 5.5 [5.0;6.0] | 0.020 | 5.0 [4.25;6.0] |
| Intraoperative ECMO weaning | 25 (61.0) | 32 (50.8) | 0.413 | 82 (62.1) |
| Intraoperative transfusion amount (mL) | 2910.0 [2100.0;5350.0] | 3100.0 [1935.0;4485.0] | 0.808 | 2030.0 [1220.0;3255.0] |
| Estimated blood loss (mL) | 2800.0 [2000.0;5000.0] | 2100.0 [1400.0;3500.0] | 0.066 | 1800.0 [1100.0;3350.0] |
| Postoperative day when the target tacrolimus level was achieved (days) | 14.0 [10.0;17.0] | 4.0 [3.0;9.0] | 0.001 | 4.0 [3.0;9.0] |
| Tacrolimus level on the day the target level was achieved (mg/dL) | 10.8 [10.5;11.6] | 12.1 [10.8;13.8] | 0.001 | 11.9 [10.8;14.0] |
| Postoperative complications | ||||
| Acute rejection | 2 (4.9) | 5 (7.9) | 0.701 | 2 (1.5) |
| AKI | 9 (22.0) | 27 (42.9) | 0.048 | 35 (26.5) |
| Infection (culture proven) | 3 (7.3) | 19 (30.2) | 0.011 | 24 (18.2) |
| Neurologic complications | 2 (4.9) | 7 (11.1) | 0.477 | 6 (4.5) |
| Gastrointestinal complications | 4 (9.8) | 14 (22.2) | 0.169 | 29 (22.0) |
| Duration of postoperative ICU stay (first admission; days) | 7.0 [5.0;12.0] | 10.0 [5.0;19.0] | 0.197 | 7.0 [5.0;13.0] |
| Duration of postoperative hospital stay (days) | 52.0 [30.0;96.0] | 53.0 [33.5;91.5] | 0.960 | 35.0 [25.0;60.5] |
| Duration of total hospital stay (days) | 109.0 [61.0;160.0] | 79.0 [55.0;121.0] | 0.126 | 40.5 [27.0;78.0] |
| Surgery-related mortality (within 30 days) | 1 (2.4) | 6 (9.5) | 0.240 | 4 (3.0) |
AKI, acute kidney injury; ICU, intensive care unit; ECMO, extracorporeal membrane oxygenation.
Data are presented as n (%).