Fig. 8.

(A) The competitive binding assay shows most of the peaks involved with ligand 3 than ligand 1, signifying that ligand 3 had a comparatively more substantial binding. (B) Molecular overlay of ligands 1 and 3 binding poses onto E protein. Shown in subset box is the superimposition of aryl groups in ligand 1 and 3 in close proximity (protein E cartoon structure was hidden for clarity).