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. 2021 Jan 21;11:609935. doi: 10.3389/fphys.2020.609935

FIGURE 5.

FIGURE 5

Blood plasma samples were taken during seated rest (Rest); immediately after the first interval exercise bout (Ex 1; HIIT and SIT only); at the end of exercise (Ex 4, end of active recovery (Active); and the end of passive recovery (Passive). Brain-derived neurotrophic factor (BDNF; n = 21), insulin-like growth factor 1 (IGF-1; n = 17), and vascular endothelial growth factor [VEGF; n = 15 (14 in SIT)] were analyzed by ELISA. Blood lactate [n = 24 (23 in SIT)] was analyzed using automated photometric analysis. Data are presented as mean ± SD. Significance (analyzed by linear mixed model, p < 0.05) between resting values and subsequent time points is denoted by *. Significant differences between protocols are denoted by $ between MICT and HIIT; between MICT and SIT; and Ω between HIIT and SIT. ND, not determined.