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. 2021 Jan;9(1):49. doi: 10.21037/atm-20-3704

Table 3. Multivariable Cox proportional of OS and DFS.

Variables OS DFS
HR (95% CI) P value HR (95% CI) P value
Anesthesia (general anesthesia) 1.28 (1.07, 2.02) <0.001 1.06 (1.03, 1.71) <0.001
Age (years) 1.04 (1.00, 1.09) 0.018 1.07 (1.02, 1.12) 0.006
AFP (>20 ng/mL) 1.57 (1.08, 2.11) 0.022 1.25 (0.84, 1.85) 0.267
Tumor encapsulation (none) 2.06 (0.76, 3.46) 0.157 NA
Tumor staging (III–IV) NA 1.12 (0.76, 1.66) 0.576
Vascular invasion (yes) 2.55 (1.34, 4.86) 0.004 1.89 (1.25, 2.84) 0.002
ASA (III–IV) 1.75 (1.04, 2.56) 0.039 1.34 (1.04, 1.69) 0.045

OS, overall survival; DFS, disease-free survival; AFP, alpha-fetoprotein; ASA, American Society of Anesthesiologists; NA, not applicable. P≤0.05 was considered statistically significant.