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. 2021 Jan;9(1):55. doi: 10.21037/atm.2020.02.38

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2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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A histopathologically confirmed intrahepatic cholangiocarcinoma (ICC) in a 44-year-old male patient. A hepatic lesion located in the left lobe of the liver shows mild-to-moderate hyperintensity on T2-weighted imaging and targetoid restriction (black ring) on an apparent diffusion coefficient (ADC) map (A,B). On pre- (C) and post-contrast (D,E,F,G) enhanced images, the nodule demonstrates rim arterial phase hyper-enhancement (D), peripheral “washout” on portal venous phase (arrow), delayed central enhancement (triangle) on transitional phase, and targetoid HBP appearance (white ring). The pathological result (H) is poorly differentiated intrahepatic cholangiocarcinoma (magnification, 10×20).