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. 2021 Jan;9(1):18. doi: 10.21037/atm-20-3810

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2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Effects of sEphB4-HSA injections on rat CNV (choroidal neovascularization) formation induced by laser. (A) Schematic diagram of the timeline of the laser application in rats, treatments, and sacrifice. (B) Morphology scheme of laser-induced CNV in rat. (C) A representative light microscopic images of CNV lesion were obtained at days 4 or 14 after laser application. Hematoxylin & eosin stain (H&E) (C), yellow line indicates the maximum thicknesses of CNV and CNV areas are outlined with white dot line. Scale bar: 100 µm. statistical analysis of thickness of rat CNV lesion (D) and CNV area in (E).