Fig. 1.

Role of CETP in LPS transfer activity between lipoproteins. DOTAGA-Bodipy-LPS transfer activity was measured between human lipoproteins and acceptor plasma from WT, PLTP KO, and CETPTg mice (n = 6 to 8). Time course of fluorescence increase reflecting the amounts of LPS transferred from human donor HDL (A) or VLDL (B) to plasma after 0, 10, 20, and 30 min of incubation at 37°C. Subsequent AUC was calculated between 0 and 30 min of incubation (right panels). Data are means ± SD. †P < 0.05 PLTP-KO versus WT, #P < 0.05 PLTP-KO versus CETPTg; Wilcoxon test. ∗P < 0.05 PLTP-KO versus WT; Kruskal-Wallis followed by Dunn's multiple comparisons test. AUC, area under curve; FU, fluorescence units.