Fig. 5.

Plasma parameters and lipoprotein profile in mice after LPS iv injection. WT (n = 13) and CETPTg (n = 12) mice were iv injected with purified LPS from E. coli O55:B5 (15.0 mg/kg BW). (A) Total cholesterol, (B) esterified cholesterol, (C) phospholipids, and (D) triglycerides were measured in plasma 1 h after injection. Data are means ± SD. ∗P < 0.05, WT versus CETPTg; Mann-Whitney test. WT (n = 7) and CETPTg (n = 7) mice were iv injected with purified LPS from E. coli O55:B5 (15.0 mg/kg BW). Plasma samples were collected before (t = 0) and 2 h after injection and pooled by genotype for FPLC analysis. Fractions were collected to measure (E) total cholesterol and (F) phospholipids. n.s., nonsignificant.