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LPS distribution and excretion after CLP. WT (n = 4 to 8) and CETPTg (n = 4 to 8) mice were challenged with CLP. LPS concentration was obtained by direct quantitation of 3-HM in (A) plasma, (B) bile, and (C) liver using tandem mass spectroscopy. Data are means ± SD. ∗P < 0.05, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001; Kruskal-Wallis followed by Dunn's multiple comparisons test. n.s., nonsignificant.
