Table 2.
6 h after CLP |
24 h after CLP |
|||
---|---|---|---|---|
WT | CETPTg | WT | CETPTg | |
Cholesterol (g/L) | 0.79 ± 0.14 | 0.81 ± 0.15 | 1.35 ± 0.22a | 1.13 ± 0.24 |
Esterified cholesterol (g/L) | 0.44 ± 0.09 | 0.45 ± 0.07 | 0.65 ± 0.15b | 0.53 ± 0.14 |
Triglycerides (g/L) | 1.20 ± 0.38 | 1.46 ± 0.46 | 1.51 ± 0.25 | 1.77 ± 0.65 |
Phospholipids (g/L) | 1.64 ± 0.26 | 1.65 ± 0.24 | 2.52 ± 0.43b | 2.06 ± 0.30 |
Glycaemia (mmol/L) | 7.91 ± 1.85 | 7.17 ± 1.98 | 4.88 ± 0.87 | 5.30 ± 3.05 |
ALT (UI/L) | 74.50 ± 25.50 | 82.56 ± 27.04 | 320.74 ± 82.94b | 299.20 ± 47.92 |
WT (n = 6 to 8) and CETPTg (n = 6 to 8) mice were challenged with CLP. Lipid parameters, glycemia, and liver injury marker alanine aminotransferase (ALT) were measured in plasma 6 and 24 h after CLP. Data are means ± SD.
P < 0.01 versus t6h; Kruskal-Wallis test with Dunn's multiple comparisons test.
P < 0.05.