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. Author manuscript; available in PMC: 2021 Feb 4.
Published in final edited form as: Sci Transl Med. 2019 Jul 17;11(501):eaav4772. doi: 10.1126/scitranslmed.aav4772

Fig. 2. Molecular features of all of the pancreatic cysts.

Fig. 2.

This heatmap shows the molecular features of the 862 patients with pancreatic cysts. Areas highlighted in black show the features present in the different types of cysts. For example, one can see that GNAS mutations occur almost exclusively in patients with IPMN and PDAC and that they occur in cysts with all grades of dysplasia. In contrast, SMAD4 mutations occur far more commonly in patients with PDAC or IPMNs with cancer or high-grade dysplasia than in patients with low- or intermediate-grade dysplasia.