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. 2021 Jan 4;45(3):921–932. doi: 10.3892/or.2021.7920

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Copyright: © Ji et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — CDCA5 knockdown inhibits ERK signalling pathway activation. (A and B) Western blotting was used to detect the total ERK protein expression levels and ERK phosphorylation levels after CDCA5 knockdown in C4-2 and PC-3 cells. GAPDH was used as an internal control. (C) Representative pictures of the protein expression levels of CDCA5, p-ERK, Ki67 and cleaved caspase-3 in patient specimens. The magnification of the images are ×200 (n=96). CDCA5, cell division cycle-associated 5; ERK, extracellular signal-regulated kinase; sh, short hairpin; CON, control; p-, phosphorylated.