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. 2020 Dec 18;45(3):933–944. doi: 10.3892/or.2020.7905

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — miR-642a-5p inhibits colon cancer cell viability by targeting COL1A1. (A) COL1A1 protein expression in DLD-1 cells after COL1A1 overexpression. (B) mRNA expression levels of miR-642a-5p and COL1A1 in DLD-1 cells. (C) Protein expression levels of COL1A1 in DLD-1 cells. (D) DLD-1 cell viability in different groups. (E) COL1A1 protein expression in SW620 cells after COL1A1 overexpression. (F) mRNA expression levels of miR-642a-5p and COL1A1 in SW620 cells. (G) Protein expression levels of COL1A1 in SW620 cells. (H) SW620 cell viability in different groups. *P<0.05 vs. OE-NC + mimic-NC group; ^#P<0.05 vs. OE-NC + mimic-miR-642a-5p group. COL1A1, collagen type I α1; miR, microRNA; NC, negative control; OE, overexpression.