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. 2021 Jan 25;6(4):2626–2637. doi: 10.1021/acsomega.0c04779

Table 1. Summary of the Characteristic FTIR Peaks Representing the Key Functional Groups in Metformin Hydrochloride and Various Lipophilic Metformin Saltsa.

metformin/metformin salts metformin–NH2 carbonyl group C=O imine C=N stretch N–H bending C–N stretch
metformin 3368.17 and 3294.06   1622.87 1544.76 1059.73
metformin–docusate 3346.99 1734.72 1639.26 1558.26 1035.63
metformin–oleate 3368.20 1737.62 1623.43 1560.19 1040.22
metformin–caprate 3361.46 1737.62 1641.19 1553.44 1047.20
metformin–laurate 3369.17 1731.83 1640.23 1554.41 1052.98
metformin–cholate 3368.20 1736.65 1651.80 1579.48 1079.98
a

The characteristic FTIR peaks of metformin show considerable shifts in the lipophilic salts of metformin, indicating the formation of metformin salts.