Figure 1.
Radiation increases the motility of NSCLC cells. (A and B) Wound healing assay for (A) A549 or (B) H1299 cells treated with 5 Gy radiation (Radiation) or incubated without radiation (Con) for 48 h. Scale bar, 100 µm. (C) Transwell Matrigel invasion assay for A549 and H1299 cells treated with 5 Gy radiation (Radiation) or incubated without radiation (Con) for 48 h. Scale bar, 100 µm. (D) E-Cad mRNA expression levels following treatment with increasing doses of radiation for 24 h. (E) E-Cad protein expression levels following treatment with 5 Gy radiation (Radiation) or incubation without radiation (Con) for 24 h. Data are presented as the mean ± SD of three independent experiments. **P<0.01. NSCLC, non-small cell lung cancer; E-Cad; E-cadherin; Con, control.