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. 2020 Dec 30;45(3):975–986. doi: 10.3892/or.2020.7916

Figure 2.

Figure 2.

Effects of compound C and siAMPK on the VSP-17-induced inhibition of migration and invasion in MDA-MB-231 and MDA-MB-453 cells. (A and B) Cells were treated with 1 µM compound C, 10 µM VSP-17 or 10 µM VSP-17 + 1 µM compound C for 24 h. Transwell assays were used to evaluate the (A) migratory and (B) invasive abilities in MDA-MB-231 and MDA-MB-453 cells. (C and D) Cells were treated with 10 µM VSP-17 or transfected with siAMPK. Transwell assays were used to evaluate the (C) migratory and (D) invasive abilities in MDA-MB-231 and MDA-MB-453. The data are expressed as the mean ± SEM of three independent experiments. **P<0.01 vs. control; &&P<0.01 vs. VSP-17. Com. C, compound C; si, small interfering RNA; AMPK, AMP-activated protein kinase.