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. 2021 Feb 3;19:36. doi: 10.1186/s12951-020-00763-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — a The Ce6 loading efficiency of LMM@BSA clay nanosheets with different concentrations; b the DO content (mg/L) of dissolved oxygen in LMM@BSA and LMM@BSA + H₂O₂ solution; c, d absorption spectrum changes of DPBF under 660 nm laser irradiation with LMM@BSA/Ce6 nanosheets c in the absence and d presence of H₂O₂ (10 mM); e viability profile of HT29 cells after different treatments; f in vitro cumulative release profiles of DOX from LMM@BSA/DOX nanosheets under different pH and temperature; g–i the calcein-AM/PI dyeing morphology of HT29 cells corresponding to e; g LMM@BSA + PTT; h LMM@BSA/Ce6 + PDT; i LMM@BSA/Ce6 + PDT + PTT