Fig. 6.

HIPK3 is a target of miR-197-3p. a, b qRT-PCR and western blot analysis of HIPK3 expression in BC tissues and matched non-tumor tissues. c, d qRT-PCR and western blot analysis of HIPK3 expression in normal MCF-10A cells, BC cell lines (T47D and MCF7), and TAM-resistant BC cell lines (T47D/TAM and MCF7/TAM). e The correlation between HIPK3 level and miR-197-3p expression in BC tissues using the Pearson correlation analysis. f The potential binding sites of HIPK3 and miR-197-3p. g Luciferase activities detection in 293 T cells co-transfected with the reporter plasmids and indicated miRNAs using the dual-luciferase reporter assay. **P < 0.01, ***P < 0.001, ^#P < 0.05, ^##P < 0.01