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. 2021 Feb 4;13:34. doi: 10.1186/s13195-021-00773-z

Table 3.

Approximate conditional analysis on tissue-specific allelic series in ACE eQTLs

Tissue of ACE eQTL P value of rs4308 conditioned on rs4324 Effect of rs4308 on the ACE eQTL conditioned on rs4324 P value of rs4324 conditioned on rs4308 Effect of rs4324 on the ACE eQTL conditioned on rs4308
Lung 0.15 0.048 2.57e−08 0.18
Cerebellum 5.34e−04 − 0.25 0.66 − 0.034
Kidney cortex 4.41e−08 0.49 0.21 − 0.14

Approximate conditional analyses performed on the leading single-tissue eQTLs at the ACE locus