Table 2.

Univariate and multivariable Cox's proportional hazard models for the background variables analyzed fitted for the need for revision ESS during the follow up of mean (min–max) 7.2 (0.9–16.2) years

	N All	N (%) ESS	HR (95% CI)	Adjusted HR (95% CI)
Gender
Female	86	39 (45.3)	1
Male	52	26 (50.0)	1.10 (0.67–1.80)
Age
≥47 years	62	27 (43.5)	1
<47 years	76	38 (50.0)	1.12 (0.68‐1.83)
LM score
<16/24	43	17 (39.5)	1
≥16/24	83	41 (49.4)	1.33 (0.75–2.34)
NP score
<4/8	21	6 (28.6)	1
≥4/8	97	49 (50.5)	2.00 (0.85–4.67)
NP eosinophilia
<30%	17	6 (35.3)	1	1
≥30%	47	31 (66.0)	2.67 (1.11–6.48)	3.21 (1.23‐8.38)
Baseline OCS courses/year
<1	66	24 (36.4)	1	1
≥1	65	38 (58.5)	1.73 (1.04‐2.89)	1.03 (0.53–2.01)
Baseline ab courses/year
<4	75	35 (46.7)	1
≥4	42	20 (47.6)	1.09 (0.63‐1.90)
Baseline total ethmoidectomy
Yes	102	9 (32.1)	1	1
No	28	52 (51.0)	2.17 (1.07–4.42)	2.50 (0.75–8.35)
Baseline start with ATAD
Yes	75	35 (46.7)	1
No	63	30 (47.6)	0.92 (0.56–1.51)

Note: Only the N‐ERD subjects who underwent ESS at the baseline (n = 138) were included. Bold values denote statistical significance at the p < .05 level. The second model is a multivariable model adjusted by the background variables that were associated with revision ESS at p < .05 level in the first model.

Abbreviations: ab, antibiotic; ATAD, AD followed by ASA treatment after desensitization; CI, confidence interval; ESS, endoscopic sinus surgeries; HR, hazard ratio; NERD, nonsteroidal anti‐inflammatory drug exacerbated respiratory disease; OCS, oral corticosteroid.