TABLE 2.

Types of CVD Events Reported

Type of CVD Reported*	Trials†
Heart failure	30 (15.9)
ACS	13 (6.9)
Atrial fibrillation	9 (4.8)
Uncontrolled HTN‡	30 (15.9)
Thromboembolic disease	34 (18.0)
CVA	26 (13.8)
Coronary revascularization§	1 (0.5)
Myocarditis	0 (0.0)
Cardiovascular death||	56 (29.6)
Other CVD¶	17 (9.0)
Multiple CVD events#	39 (20.6)

Values are n (%).

^*The sum of the trial excluded is >100% and greater than the overall number of excluded trials because several studies used multiple exclusion criteria.

^†The percentages reported reflect a denominator of 189.

^‡Usually defined as >150/90 mm Hg, consistent with mild (i.e., stage 1) hypertension by the available contemporary guidelines.

^§No trials reported peripheral revascularizations.

^||Includes those with sudden cardiac death or coronary artery disease–related death or any other mention of cardiovascular death.

^¶Other CVD included valvular disease, myocarditis, or other mention of cardiovascular disease

^#Trials where multiple types of CVD events (e.g., ACS, and heart failure) were reported. ACS = acute coronary syndrome; CVA = cerebrovascular accident;

ACS = acute coronary syndrome; CVA = cerebrovascular accident; CVD = cardiovascular disease; HTN = hypertension.