Table 3. Comparison of 24 h urine protein, ACR, urinary n-acetyl-β-d-(NAG)/creatinine (Cr), urinary β2 globulin (B2-MG)/creatinine, urinary α1 globulin (A1-MG)/creatinine between treatment and non- treatment groups, and before and after treatment (means±SD).
Time | Group | 24h urine protein (g/L) | ACR (mg/mmol) | urine NAG/Cr (U/mmol) | Urine β2-MG/Cr (mg/mmol) | Urine α1-MG/Cr (mg/mmol) |
---|---|---|---|---|---|---|
Before treatment | Treatment | 4.15±2.58 | 439.62±79.10 | 3.75±0.92 | 159.32±61.25 | 4.26±0.54 |
Non-treatment | 4.02±2.67 | 441.06±78.52 | 3.54±0.83 | 161.19±62.01 | 4.31±0.52 | |
Treatment at four weeks | Treatment | 3.17±2.65* △ | 331.56±76.45* △ | 2.71±0.89* △ | 131.12±60.93* △ | 3.18±0.49* △ |
Non-treatment | 4.10±2.58 | 441.45±78.68 | 3.59±0.82 | 161.42±62.19 | 4.37±0.50 | |
Eight weeks | Treatment group | 2.85±0.89* △ | 201.06±78.82* △ | 1.65±0.90* △ | 98.22±60.41* △ | 1.97±0.51* △ |
Non-treatment | 4.21±2.66 | 442.96±79.04 | 3.63±1.01 | 162.05±61.97 | 4.45±0.53 | |
Twelve weeks | Treatment | 2.80±1.59* △ | 191.06±92.12* △ | 1.71±0.46* △ | 106.01±80.01* △ | 1.83±0.61* △ |
Non-treatment | 4.81±2.09 | 501.32±79.65 | 3.90±1.81 | 222.05±49.31 | 5.12±1.09 | |
Twenty four weeks | Treatment | 3.07±1.21* △ | 191.06±92.12* △ | 2.32±1.06* △ | 126.01±60.98* △ | 2.08±0.30* △ |
Non-treatment | 4.26±2.45 | 491.65±70.99 | 4.58±1.11 | 282.71±99.43 | 4.92±2.41 |
Significant difference between treatment and non-treatment groups (P<0.05);
significant differences before and after treatment in the treatment group (P<0.05).