Table 5. Markers of iron status of IL-6 (-174 G/C, -572 G/C and -597 G/A) genotypes in HCV-negative HD patients.
| Hemoglobin | Hematocrit | RBCs | MCV | MCH | MCHC | Ferritin | Iron | Hepcidin | |
|---|---|---|---|---|---|---|---|---|---|
| IL-6 (-174) | |||||||||
| GG | 9.41± 1.56 | 27.22± 3.98 | 3.28±0.43 | 83.27± 6.63 | 28.62±2.64 | 34.42± 1.86 | 896.06 ±628.30 | 295.22±106.17 | 331.09±78.14 |
| GC | 8.05± 1.84 | 25.14 ±9.20 | 4.58 ±6.84 | 84.14 ±7.07 | 28.31 ±2.91 | 33.76 ±1.98 | 1028.39 ±560.03 | 419.64±219.34 | 640.18± 399.44 |
| P value | NS | NS | NS | NS | NS | NS | NS | NS | P<0.05 |
| IL-6 (-572 G/C) | |||||||||
| GG | 8.16 ±1.81 | 25.28± 9.02 | 3.72 ±4.93 | 84.40 ±6.59 | 28.52± 2.57 | 33.91 ±1.80 | 1075.51± 546.50 | 422.77± 199.54 | 590.86 ±385.79 |
| GC | 8.74 ±1.82 | 26.06 ±5.49 | 6.53 ±9.56 | 82.55± 8.68 | 27.73 ±3.94 | 33.59± 2.53 | 633.99± 650.37 | 295.88± 208.48 | 516.53 ±370.94 |
| CC | 11.7 | 32.1 | 3.96 | 81.1 | 29.5 | 36.4 | 1532.21 | 193 | 376.74 |
| P value | NS | NS | NS | NS | NS | NS | NS | NS | NS |
| IL-6 (-597 G/A) | |||||||||
| GG | 8.35± 1.97 | 24.53 ±5.47 | 4.88 ±7.16 | 83.41 ±7.33 | 28.24± 3.03 | 33.95 ±2.10 | 1015.30± 516.62 | 403.57± 192.25 | 566.82 ±363.55 |
| GA | 8.39± 1.63 | 28.13± 12.73 | 2.93 ±0.58 | 85.20± 5.88 | 28.73±2.37 | 33.82 ±1.66 | 959.71± 704.35 | 363.83±239.40 | 579.57 ±419.08 |
| AA | - | - | - | - | - | - | - | - | - |
| P value | NS | NS | NS | NS | NS | NS | NS | NS | NS |
All data are presented as mean ± SD. N: number of cases, RBCs: Red blood cells count, MCV: Mean corpuscular volume, MCH: Mean corpuscular hemoglobin, MCHC: Mean corpuscular hemoglobin concentration, and NS: non-significant. Differences among the groups were compared by ANOVA. P < 0.05 is considered significant.