Table 5.

Predicting the impact of mutations on proteins from different set of genomes.

		Original congregation			Asymptomatic			Deceased
No of Samples		611			30			15
Samples with no mutation		156			0			01
Total Variants		281			55			13
Mutation Type	Protein Prediction by tools	No of variants	p value	Sum of Mutation Incidence	No of variants	p value	Sum of Mutation Incidence	No of variants	p value	Sum of Mutation Incidence
NEUTRAL	Three Tools (N3)	133	0.47	254	31	0.56	76	2	0.15	4
	Two Tools (N2)	65	0.23	160	18	0.33	60	6	0.46	10
	Total = (N3 + N2)	198	0.7	414	49	0.89	136	8	0.61	14
DISEASE	Three Tools (D3)	41	0.15	187	2	0.04	4	1	0.08	2
	Two Tools (D2)	42	0.15	70	4	0.07	2	4	0.31	6
	Total = (D3 + D2)	83	0.3	257	6	0.11	6	5	0.39	8
	Grand Total	281	1	671	55	1	142	13	1	22