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. 2021 Feb 4;21(3):361–367. doi: 10.1007/s10238-021-00687-y

Table 3.

Clinical features, laboratory data and chest CT scan in the follow-up

Total (n = 51) Positive cases (n = 25) Negative cases (n = 26) p value
Fever (temperature ≥ 37.3 °C) 0 (0%) 0 (0%) 0 (0%)
Cough 27 (52.9%) 11 (44.0%) 6 (23.1%) 0.113
Fatigue 0 (0%) 0 (0%) 0 (0%)
Lymphocyte count below the normal range 2 (3.9%) 2 (8%) 0 (0%) 0.912
IgG, S/CO 15.62 (3.81–33.45) 9.55 (2.24–25.65) 25.09 (5.92–84.50) 0.027
 ≤ 10 20 (39.2%) 13 (52.0%) 7 (26.9%) 0.110
 > 10 to ≤ 30 17 (33.3%) 8 (32.0%) 9 (34.6%)
 > 30 14 (27.5%) 4 (16.0%) 10 (38.5%)
IgM, S/CO 1.70 (0.52–4.91) 0.63 (0.39–3.82) 2.46 (0.93–5.33) 0.011
 ≤ 1 23 (45.1%) 16 (64.0%) 7 (26.9%) 0.027
 > 1 to ≤ 10 20 (39.2%) 6 (24.0%) 14 (53.8%)
 > 10 8 (15.7%) 3 (18.0%) 5 (19.2%)
IL-2 (normal range ≤ 7.5 pg/mL) 0.00 (0.00–0.02) 0.00 (0.00–0.06) 0.00 (0.00–0.01) 0.206
IL-6 (normal range ≤ 5.4 pg/mL) 1.61 (1.08–2.27) 1.61 (0.60–2.45) 1.57 (1.30–2.08) 0.832
IL-8 (normal range ≤ 20.6 pg/L) 4.17 (1.80–7.39) 4.17 (1.45–8.16) 3.83 (1.89–6.38) 0.903
IL-1B(normal range ≤ 12.4 pg/mL) 0.16 (0.00–0.94) 0.00 (0.00–0.84) 0.49 (0.00–0.96) 0.456
IFN-γ(normal range ≤ 23.1 pg/mL) 1.51 (0.68–2.92) 1.12 (0.54–2.97) 1.80 (1.12–2.84) 0.550
During of viral shedding, days 18.0 (9.0–35.5) 36.0 (30.0–43.0) 9.0 (7.0–11.0) 0.000
Imaging features
 Consolidation 3 (5.9%) 2 (8.0%) 1 (3.8%) 0.972
 Ground-glass opacity 33 (64.7%) 15 (60.0%) 18 (69.2%) 0.490
 Bilateral infiltration 32 (62.7%) 14 (56.0%) 18 (59.2%) 0.329

Data are given as n (%) or median (IQR)

S/CO signal/cut-off, ↓ below normal range, Ig immunoglobulin, CT computed tomography, IL interleukin, IFN interferon