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. Author manuscript; available in PMC: 2021 Feb 4.
Published in final edited form as: Anal Chem. 2020 Nov 9;92(23):15489–15496. doi: 10.1021/acs.analchem.0c03372

Figure 3.

Figure 3.

Enhanced collision induced unfolding comparison of bovine serum albumin (BSA) CIU from a (A) TWIM-MS vs a (B) DTIMMS. Higher pre-IM activation is achievable on the DTIM-MS as evidenced by the fifth feature at higher CCS observed on the DTIMMS. (C) Median CCS of each feature from TWIM and DTIM CIU experiments. (D) ΔCCS between features from the TWIM and DTIM CIU experiments.