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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Gynecol Oncol. 2020 Dec 6;160(2):464–468. doi: 10.1016/j.ygyno.2020.11.024

Table 1.

ERAS Premedication Ordering Guidelines

Medication Guidelines
Pregabalin
  • CI if hypersensitivity

  • Avoid in patients older than 75 years of age

Celecoxib
  • CI if hypersensitivity (not sulfa allergy)

  • CI if active GI bleeding

  • CI with CrCI < 30 mL/min

  • CI if Child-Pugh Class C

  • CI in patients with NYHA functional classification II and above

  • Decrease dose to 200 mg for Child-Pugh Class B

Tramadol ER
  • CI if hypersensitivity

  • CI if CrCI < 30 mL/min

  • CI if Child-Pugh Class C

  • CI with concurrent MAOI therapy

  • Decrease dose to 200 mg for Child-Pugh Class B

Acetaminophen
  • CI if hypersensitivity

  • Decrease dose if patient weight < 50 kg (dose 15 mg/kg)

  • Decrease dose to 500 mg if hepatic impairment/active hepatic disease, alcoholism, chronic malnutrition, severe hypovolemia, or CrCI < 30 mL/min

CI: contraindicated, GI: gastrointestinal, NYHA: New York Heart Association, ER: extended release, MAOI: monoamine oxidase inhibitor, CrCl: creatinine clearance