Table 2.
Clinical and demographic characteristics by acetaminophen statusa
| Characteristic | Overall N = 353 | Intravenous n = 178 (50.4%) | Oral n = 175 (49.6%) | p-value |
|---|---|---|---|---|
| Age, median (Min, Max) | 60 (20, 86) | 59.5 (22, 82) | 60 (20, 86) | 0.79 |
| Charlson Comorbidity Index, median (Min, Max) | 3 (0, 9) | 3 (0, 9) | 3 (0, 8) | 0.89 |
| Length of stay (days), median (Min, Max) | 3 (1, 25) | 3 (1, 25) | 3 (1, 12) | 0.82 |
| Surgical time (minutes), median (Min, Max) | 212 (46, 846) | 202.5 (46, 840) | 217 (72, 619) | 0.032 |
| Time in PACU (hours), median (Min, Max) | 3.33 (1.1, 9.8) | 3.4 (1.2, 9.8) | 3.22 (1.1, 7.72) | 0.56 |
| BMI (kg/m2), median (Min, Max) | 27.7 (15.8, 62.7) | 27 (19.3, 62.7) | 28.2 (15.8, 54) | 0.89 |
| ASA physical status | 0.11 | |||
| I/II | 21 (6%) | 7 (3.9%) | 14 (8%) | |
| III/IV | 332 (94%) | 171 (96.1%) | 161 (92%) | |
| Indication for surgery | 0.96 | |||
| Malignant | 276 (78.2%) | 139 (78.1%) | 137 (78.3%) | |
| Benign | 77 (21.8%) | 39 (21.9%) | 38 (21.7%) | |
| Intraoperative dexamethasone dose (mg), median (Min, Max) | 8 (0, 20) | 10 (0, 20) | 8 (0, 10) | 0.004 |
| Wound infiltration compliance | 346 (98%) | 176 (98.9%) | 170 (97.1%) | 0.28 |
| General Anesthesia Technique | 0.001 | |||
| Volatile (inhaled) | 150 (42.4%) | 54 (30.3%) | 96 (54.9%) | |
| Total intravenous | 70 (19.8%) | 48 (27%) | 22 (12.6%) | |
| Combined | 133 (37.7%) | 76 (42.7%) | 57 (32.6%) | |
| ERAS compliance %, median (Min, Max) | 75 (45, 90) | 70 (55, 85) | 80 (45, 90) | <0.001 |
| Standard premedication complianceb | 0.009 | |||
| No | 116 (32.9%) | 47 (26.4%) | 69 (39.4%) | |
| Yes | 237 (67.1%) | 131 (73.6%) | 106 (60.6%) |
a
N (%) reported unless indicated otherwise; missing values not included in p-value calculation.
b
Patients receiving all premedication medications (pregabalin, celecoxib, and tramadol)
ASA: American Society of Anesthesiologists, BMI: body mass index