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. Author manuscript; available in PMC: 2021 Feb 4.
Published in final edited form as: Exp Gerontol. 2019 Dec 5;130:110805. doi: 10.1016/j.exger.2019.110805

Figure 2.

Figure 2.

A-B. Representative images of β-galactosidase staining in BMSCs treated with indicated doses of KYN for 3 and 24h. Data are expressed as β-gal-positive staining area percentage and are representative of at least 3 independent experiments. * p< 0.05 vs. 0μM KYN; ** - p< 0.05 vs. KYN 100μM at 3 hr. treatment. C., D. – Expression of p21 and p16 in BMSCs treated with indicated doses of KYN for 24 hr. Data are expressed as protein/β-actin ratio adjusted to 0μM KYN. * p< 0.05 vs. 0 μM KYN. E. SAHP detection by Histone 3-methyl-9K nuclear staining in BMSCs treated with indicated doses of KYN for 24h. Nuclei were stained with DAPI (blue). All data are representative of at least 3 independent experiments.