TABLE 1.
Subgroup Ranking a | Subgroup description | Coverage Discovery/Test | Adjusted odds-ratios (IC95%) Discovery b | p-value Discovery | Adjusted p-value Discovery c | Adjusted odds-ratios (IC95%) Test b | p-value Test | Adjusted p-value Test c |
---|---|---|---|---|---|---|---|---|
S1 | Last postprandial glucose measurement (mg/dL) 172.0 | 30%/27% | 4.78 [3.5; 6.5] | 1.81E-23 | 1.15E-18 | 4.28 [3.2; 5.7] | 2.09E-24 | 1.04E-23 |
S2 | Last fasting blood glucose measurement (mg/dL) 129.6 | 38%/36% | 3.60 [2.8; 4.7] | 9.86E-21 | 6.28E-16 | 5.06 [4.0; 6.5] | 9.82E-37 | 9.82E-36 |
S3 | Follow healthy diet and exercise plan = Yes AND Device used for insulin: Vials and syringes = No AND Cumulated # of individual therapies taken by the patient 3 | 14%/16% | 2.57 [1.9; 3.5] | 7.08E-9 | 4.50E-4 | 2.50 [1.9; 3.3] | 1.78E-11 | 3.84E-11 |
S4 | Follow healthy diet and exercise plan = Yes AND Device used for insulin: Vials and syringes = No AND # of different cardiovascular treatments 2 | 22%/17% | 2.26 [1.7; 3.0] | 9.96E-9 | 6.34E-4 | 2.36 [1.8; 3.0] | 5.24E-11 | 7.48E-11 |
S5 | Follow healthy diet and exercise plan = Yes AND # of OGLD 1 AND Type of health insurance = Public | 16%/24% | 2.47 [1.8; 3.4] | 1.05E-8 | 6.69E-4 | 2.44 [1.9; 3.1] | 2.20E-13 | 7.33E-13 |
S6 | Follow healthy diet and exercise plan = Yes AND Covered by a health insurance = Yes AND # of different cardiovascular treatments 2 | 17%/11% | 2.34 [1.7; 3.1] | 1.28E-8 | 8.15E-4 | 1.81 [1.3; 2.5] | 1.42E-4 | 1.58E-4 |
S7 | Follow healthy diet and exercise plan = Yes AND Covered by a health insurance = Yes AND Cumulated # of individual therapies taken by the patient 4 | 17%/16% | 2.33 [1.7; 3.1] | 1.30E-8 | 8.27E-4 | 2.44 [1.9; 3.2] | 1.92E-11 | 3.84E-11 |
S8 | Follow healthy diet and exercise plan = Yes AND Times seen by a diabetologist in the past 3 months = 0 AND Cumulated # of individual therapies taken by the patient 4 | 16%/17% | 2.43 [1.8; 3.3] | 1.85E-8 | 1.18E-3 | 2.25 [1.7; 3.0] | 5.46E-9 | 6.82E-9 |
S9 | Follow healthy diet and exercise plan = Yes AND Covered by a health insurance = Yes AND Treated for other form of dyslipidemia = Yes | 22%/19% | 2.33 [1.7; 3.2] | 1.94E-7 | 1.24E-2 | 2.64 [2.0; 3.5] | 4.87E-11 | 7.48E-11 |
S10 | Follow healthy diet and exercise plan = Yes AND Covered by a health insurance = Yes AND Received biguanides = No | 12%/8% | 2.40 [1.7; 3.3] | 2.66E-7 | 1.70E-2 | 1.86 [1.3; 2.6] | 3.07E-4 | 3.07E-4 |
Subgroup ranking is based on p-values on discovery dataset.
Odds-ratios are adjusted for confounding factors through multiple regression model.
Adjusted p-values for multiple testing are based on a Bonferroni correction (resp. Benjamini-Hochberg procedure) on the discovery dataset (resp. on the test dataset).