TABLE 5.

Credibility metrics from literature (used in Q-Finder) computed on APRIORI-SD results.

Subgroup Ranking a	Subgroup description	Coverage Discovery/Test	Adjusted odds-ratios (IC95%) Discovery b	p-value Discovery	Adjusted odds-ratios (IC95%) Test b	p-value Test	Adjusted p-value Test c
S1	Last postprandial glucose measurement (mg/dL) $\le$ 144 AND Self monitoring testing performed at bed time = No	15%/12%	4.73 [3.5; 6.5]	2.17E-22	3.80 [2.8; 5.1]	6.12E-19	1.03E-18
S2	Last postprandial glucose measurement (mg/dL) $\le$ 144 AND Self monitoring testing performed at bed time = No AND # of sorts of required hospitalization (macro/microvascular, hypo) = 0	15%/12%	4.73 [3.5; 6.5]	2.17E-22	3.76 [2.8; 5.1]	2.39E-18	3.42E-18
S3	Last postprandial glucose measurement (mg/dL) $\le$ 144 AND # of sorts of required hospitalization (macro/microvascular, hypo) = 0	16%/13%	4.65 [3.4; 6.4]	4.82E-22	4.21 [3.1; 5.6]	3.97E-22	1.99E-21
S4	Last postprandial glucose measurement (mg/dL) $\le$ 144	16%/13%	4.65 [3.4; 6.4]	4.82E-22	4.31 [3.2; 5.8]	3.24E-23	3.24E-22
S5	Last postprandial glucose measurement (mg/dL) $\le$ 144 AND Self monitoring testing performed at bed time = No AND Receives GLP-1 analogues = No	15%/12%	4.81 [3.5; 6.6]	1.78E-22	3.67 [2.7; 5.0]	2.14E-17	2.37E-17
S6	Last postprandial glucose measurement (mg/dL) $\le$ 144 AND Receives amylin agonist = No AND Receives GLP-1 analogues = No	15%/13%	4.73 [3.5; 6.5]	4.15E-22	4.19 [3.1; 5.6]	1.14E-21	3.52E-21
S7	Last postprandial glucose measurement (mg/dL) $\le$ 144 AND Receives GLP-1 analogues = No AND # of sorts of required hospitalization (macro/microvascular, hypo) = 0	15%/13%	4.73 [3.5; 6.5]	3.95E-22	4.07 [3.0; 5.5]	1.67E-20	3.34E-20
S8	Follow healthy diet and exercise plan = Yes AND Times seen by a diabetologist in the past 3 months = 0 AND Cumulated # of individual therapies taken by the patient $\le$ 4	15%/13%	4.73 [3.5; 6.5]	3.95E-22	4.17 [3.1; 5.6]	1.41E-21	3.52E-21
S9	Last postprandial glucose measurement (mg/dL) $\le$ 144 AND Self monitoring testing performed at bed time = No AND Receives amylin agonist = No	15%/12%	4.7 [3.4; 6.4]	3.86E-22	3.72 [2.8; 5.0]	3.74E-18	4.68E-18
S10	Follow healthy diet and exercise plan = Yes AND Receives more than 2 OGLD = No AND Patient living in = Urban area	42%/25%	2.6 [2.0; 3.4]	1.01E-12	2.41 [1.9; 3.0]	1.10E-14	1.10E-14

^aSubgroup ranking is the same as in Table 2

^bOdds-ratios are adjusted for confounding factors through multiple regression model

^cAdjusted p-values for multiple testing are based on Benjamini-Hochberg procedure on the test dataset