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. 2021 Feb 4;16(2):e0244325. doi: 10.1371/journal.pone.0244325

Table 1. Factors exhibiting clinical relevance.

Surgical treatment Biopsy
Age (mean)
42.21 50.61
p = 0.053
Tumor volume (mean)
26.28 32.13
p = 0.255
Ki-67 proportions (mean)
18.95 28.35
p = 0.007
Tumor components (n)
Cystic 0 1
Solid 8 12
Solid & cystic 11 10
p = 0.635
Ventricle wall enhancement (n)
Yes 0 16
No 19 7
p = 2.01E-06
Multiple lesions (n)
Yes 0 7
No 19 16
p = 0.011
Brainstem extension (n)
Yes 12 8
No 7 15
p = 0.128
Tumor location (n)
Anterior 3 2
Lateral 3 1
Lateral posterior inferior 6 4
Medial 3 4
Medial posterior inferior 2 5
Posterosuperior 2 7
p = 0.4
Motor symptoms (n)
Yes 16 23
No 3 0
p = 0.084
Sensory symptoms (n)
Yes 6 8
No 13 15
p = 1.0
Language symptoms (n)
Yes 1 3
No 18 20
p = 0.614
Visual symptoms (n)
Yes 5 5
No 14 18
p = 1.0
Cognitive symptoms (n)
Yes 10 16
No 9 7
p = 0.421
MGMT status (n)
Methylated 10 7
Un-methylated 9 16
p = 0.253

Mean values were analyzed using t-test and all other measures were analyzed using the chi-squared or Fisher’s exact tests. Bold indicates significant results(p-value<0.05). MGMT, O6-methylguanine- DNA methyltransferase