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. 2021 Feb 4;16(2):e0246296. doi: 10.1371/journal.pone.0246296

Table 2. Prognostic factors associated with in-hospital mortality.

Univariate analysis
Variables OR 95% CI P
Age 1.043 1.019–1.068 <0.000
Male 0.717 0.383–1.343 0.299
IC group with HIV 0.175 0.058–0.531 0.002
IC group without HIV 1.783 0.863–3.684 0.118
Non-IC group 3.191 0.963–10.570 0.058
Cardiovascular disease 1.195 0.452–3.159 0.720
Interstitial lung disease 0.138 0.030–0.640 0.011
Dyspnea 2.803 1.526–5.148 0.001
C-reactive protein 1.001 0.990–1.011 0.870
AaDO2 1.003 1.001–1.005 0.007
P/F ratio 0.988 0.980–0.997 0.006
Lactate dehydrogenase 1.000 1.000–1.000 0.831
Interval between admission and anti-PCP treatment 1.044 0.978–1.116 0.195
Multivariate analysis
Variables OR 95% CI P
Age 1.060 1.024–1.104 0.001
AaDO2 1.002 1.000–0.005 0.016
Dyspnea 3.625 1.052–12.489 0.041

AaDO2, alveolar-arterial oxygen pressure difference; CI, confidence interval; HIV, human immunodeficiency virus; IC, immunocompromised; OR, odds ratio; PCP, Pneumocystis jirovecii pneumonia; P/F, PaO2/FiO2.