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Survival of mice of the indicated genotypes maintained under chronic hypoxia (10% O2). A, Lifespan data for mice of the indicated SDHC TH‐Cre genotypes over 80 weeks. Data represent 23 FFCx and 18 F + Cx males; 16 FFCx and 16 F + Cx females. B, Lifespan data for mice of the indicated genotypes expressing a dominant negative p53 allele in TH+ cells over 80 weeks. Data represent 14 FFCx and 14 F + Cx males; 15 FFCx and 14 females. Data analysis was conducted in Prism 8
