Table 4. Substitutions rates in coevolving groups of sites have changed concordantly in the evolution of Metazoa and Fungi.

No. of proteins that have changed their substitution rates concordantly	5	4 or more	3 or more	2 or more	1 or more	0 or more
Observed no. of branches with this no. of changes	6	10	23	47	131	1562
Expected no. of branches with this no. of changes	0.2	1.0	5.0	27.8	183.1	1562
p-value	<1e-4	<1e-4	<1e-4	<1e-4	1	1