TABLE 1.
| Differentially expressed gene products significantly impacted by testosterone (T) and/or Western-style diet (WSD). | |||
|---|---|---|---|
| T | WSD | T + WSD | |
| C | 251↓/218↑ | 233↓/292↑ | 266↓/283↑ |
| T | 584↓/921↑ | ||
| WSD | 380↓/421↑ | 514↓/449↑ | |
| Interaction: (WSD_T - Chow_T)-(WSD_C - Chow C) or (WSD_T-WSD_C)-(Chow_T-Chow_C) | 502↓ | ||
| 607↑ | |||
| Numbers of gene products (based on ensembl ID) significantly down-regulated (↓) or up-regulated (↑) when the group in the top row is contrasted with the group in the first column (See materials and methods for details). | |||
| Gene products with the greatest fold change (FC) in each contrast | ||||
|---|---|---|---|---|
| Contrast | Up-regulated | FC* | Down-regulated | FC* |
| T vs. C | MT-ATP8: mitochondrially encoded ATP synthase 8 | 3.093 | CRYAA/ CRYAA2: crystallin alpha A | −2.9 |
| WSD vs. C | NUDT2: nudix hydrolase 2 | 2.158 | C16orf89: thyroid transcript | −5.371 |
| T+WSD vs. C | CKM: M-type creatine kinase | 5.9 | CRYAA/ CRYAA2: crystallin alpha A | −15 |
| T+WSD vs. T | KRT2: Keratin 2 | 5.72 | PRAME: preferentially expressed antigen in melanoma | −5.485 |
| T+WSD vs. WSD | MYH7: myosin heavy chain 7 (cardiac) | 5.103 | CRYAA/ CRYAA2: crystallin alpha A | −3.972 |
| T vs. WSD | FFAR4: free fatty acid receptor 4 | 3.471 | CRYAA/ CRYAA2: crystallin alpha A | −3.012 |
*
FC is presented in log2 scale.