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. 2021 Jan 15;16(1):8–15. doi: 10.17085/apm.20089

Table 3.

Surgical Stress according to Procedures and Recommended Dosing of Glucocorticoid [7]

Type of surgery Estimated cortisol secretion rate Examples Recommended dosing
Superficial 8–10 mg/day Dental surgery Usual daily dose
Biopsy
Minor 50 mg/day Inguinal hernia repair Usual daily dose plus
Colonoscopy
Uterine curettage Hydrocortisone 50 mg IV before incision
Hand surgery Hydrocortisone 25 mg IV every 8 h × 24 h
Moderate 75–150 mg/day Lower extremity revascularization Then usual daily dose
Total joint replacement
Cholecystectomy
Colon resection
Abdominal hysterectomy
Major 75–150 mg/day Esophagectomy Usual daily dose plus
Total proctocolectomy Hydrocortisone 100 mg IV before incision
Major cardiac/vascular surgery Followed by continuous IV hydrocortisone 200 mg (> 24 h)
Hepaticojejunostomy or
Delivery Hydrocortisone 50 mg IV every 8 h × 24 h
Trauma Taper dose by half per day until usual daily dose reached

IV: intravenously.