Table 1.
Allosure | Prospera | |
---|---|---|
Number of SNPs | 266 | 13 962 |
Limit of detection | 0.16% (Grskovic et al) | 0.15% (related donors) 0.23% (unrelated donors) (Altug et al) |
Limit of quantification | 0.2% (Grskovic et al) | 0.15% (related donors) 0.23% (unrelated donors) (Altug et al) |
Sensitivity | 0.45 (Melancon) 0.59 (Bloom et al) | 0.55 (Melancon) 0.887 (Sigdel et al) |
Specificity | 0.85 (Melancon) 0.85 (Bloom et al) | 0.69 (Melancon) 0.726 (Sigdel et al) |
Coefficent of variation | 7.7% (dd-cfDNA < 2%) 4.5% (dd-cfDNA ≥ 2%) (Grskovic et al) | 4.29% (Altug et al) |
dd-cfDNA, donor-derived cell-free DNA.