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. 2021 Jan 22;10:575084. doi: 10.3389/fcimb.2020.575084

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Copyright © 2021 Chen, Ma, Li, Shen, Zhu, Zhang, Guo, Zhou and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Alterations in the fecal bacterial microbiome in the study. (A) Species accumulation curve for the fecal samples. (B) Unweighted UniFrac principal coordinate analysis (PCoA) and analysis of similarities (ANOSIM) of the bacterial microbiome in the type 2 diabetes (T2D) group (N=17) and Ctrl group (N=20) taxonomic cladogram (C) and LDA (D) were obtained using LEfSe of the 16S sequences in the type 2 diabetes (T2D) group (in blue) and Ctrl group (in orange). (E) Significantly altered bacterial genera in the T2D group. *p < 0.05, **p < 0.01, ***p < 0.001.