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. 2021 Jan 22;11:618262. doi: 10.3389/fphar.2020.618262

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Copyright © 2021 An, Lin, Li, Kong, Lou, Wu and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enrichment analysis of the key targets of the flavonoids against liver fibrosis. (A) GO enrichment analysis of the 82 key targets. Biological processes, cellular components, and molecular function terms were performed on the targets. The top significant (the cutoff criterion for a significant difference was p < 0.05) GO categories are shown. (B) KEGG enrichment analysis of the 82 key targets. The top 20 KEGG pathway enrichments are displayed, and only terms with FDR < 0.05 were selected for analysis. (C) Compound-target-pathway network. The red round nodes represent the top ten pathways, the green round nodes represent the flavonoids, and the blue triangles represent the related targets.