Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 4;11:3070. doi: 10.1038/s41598-021-82496-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Analysis of dual-pulse TMS (experiments 1 and 2). MEP amplitudes were measured peak-to-peak and indicated in percentage to the MEP generated while only stimulating the primary motor cortex (M1) with a test pulse (TP). Conditioning pulses over PMd were administered before the TP over M1 within a dual-pulse PMd-M1 paradigm (a and b). Conditioning pulses were given over the cerebellum prior to TP M1 stimulation within the dual-pulse cerebello-M1 paradigm (c and d). Error bars indicate standard error of mean. Graphs are marked with * when comparison of values with student t-test resulted in p value < 0.05 (Bonferroni–Holm-corrected). (a) Significant increase of PMd-M1 interaction only after rTMS intervention (p = 0.004). (b) Increase of PMd-M1 interaction after rTMS intervention without significance (p = 0.250). (c) Significant increase of cerebello-M1 interaction after rTMS intervention (p < 0.001) (d) Increase of cerebello-M1 interaction after rTMS intervention with a trend to significance (p = 0.057). MEP motor evoked potential, TP test pulse over primary motor cortex, PMd dorsal premotor cortex, M1 primary motor cortex, PAS paired associative stimulation, rTMS repetitive transcranial magnetic stimulation, cTBS continuous theta-burst, tDCS transcranial direct current stimulation, ISI interstimulus interval.