Table 1.
Trait | NGT | T2D | p value |
---|---|---|---|
N = 3754 | N = 3175 | – | |
Women, n (%) | 1336 (35.6) | 1368 (43.1) | 1.3 × 10–13 |
Age, (years) | 43.4 ± 8.1 | 55.9 ± 9.5 | 1.9 × 10–16 |
BMI, (kg/m2) | 28.0 ± 4.2 | 29.5 ± 4.8 | 1.0 × 10–13 |
FPG (mmol/l)a | 4.5 ± 0.5 | 7.0 ± 3.1 | 8.6 × 10–41 |
HbA1c (%)b | 5.3 ± 0.3 | 6.2 ± 1.1 | 1.0 × 10–24 |
Rs79783591 T allele frequency, (%) | 0.81 | 1.21 | 0.018 |
Rs79783591 A/A, n (%) | 3 694 (98.40) | 3 099 (97.61) | 0.060 |
Rs79783591 A/T, n (%) | 59 (1.57) | 75 (2.36) | |
Rs79783591 T/T, n (%) | 1 (0.027) | 1 (0.031) |
Data are expressed as mean ± standard deviation and N (%). NGT, normal glucose tolerance; T2D, type 2 diabetes; BMI, body mass index; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c. The difference in sex ratios was analyzed using the X2 test. Differences in means were analyzed using Student's t-tests. Significant p values (p < 0.05) are reported in bold. aFPG values were available in 3754 NGT and 376 T2D participants.
bHbA1c values were available in 1620 NGT and 246 T2D participants.