Table 1.

Characteristics of cardiovascular risk assessment models used in the study.

	Framingham Risk Scores (FRSs)		Systematic COronary Risk Evaluation (SCORE)	American College of Cardiology/American Heart Association Pooled Cohort Equations
Characteristics	ATPIII hard coronary heart disease (FRSCHD)	Cardiovascular diseases generally (FRSCVD)	High-risk algorithm	Original (PCE)	Revised (RPCE)
Year of development	2002	2008	2003	2013	2018
Age group for which applicable (years)	30–75	30–75	40–65	40–79	40–79
Populations for which was validated	Predominantly individuals of Western European descent living in United States of America		European countries with high CVD risk (e.g.: Hungary)	Multiethnic cohorts living in United States of America
Parameters included	Age, gender, total cholesterol, HDL-cholesterol, systolic blood pressure, BP treatment, and smoking status	Age, gender, total cholesterol, HDL-cholesterol, systolic blood pressure, BP treatment, diabetes, and smoking status	Age, gender, total cholesterol, HDL-cholesterol, systolic blood pressure, smoking status	Age, gender, race, total cholesterol, HDL-cholesterol, systolic blood pressure, BP treatment, diabetes, and smoking status
Parameters excluded	Diabetes status, family history of CVD	Family history of CVD	BP treatment, diabetes status, family history of CVD	Family history of CVD
Endpoints	CHD death and nonfatal MI	CHD death, nonfatal myocardial infarction, coronary insufficiency or angina, fatal or nonfatal stroke, and heart failure	Fatal atherosclerotic CVD events (including CHD, arrhythmia, heart failure, stroke, aortic aneurysm, and peripheral vascular disease)	CHD death, nonfatal MI, fatal stroke, nonfatal stroke