Table 3.

Univariable and multivariable Cox Regression Analysis of the associations between HDL-Sz and HDL-C/P ratio with cardiovascular death.

	HDL-Sz		HDL-C/P ratio
	HR (95% CI)	P value	HR (95% CI)	P value
Unadjusted	1.36 (1.16–1.58)	< 0.001	1.06 (1.03–1.09)	< 0.001
Multivariable adjustment
Model 1	1.21 (1.01–1.47)*	0.041	1.04 (1.01–1.07)*	0.008
Model 2	1.22 (1.01–1.47)*	0.041	1.04 (1.01–1.07)*	0.008

Hazard ratios for HDL-Sz reflect 1 SD change in a given measure.

Model 1 Adjusted for age, sex, BMI, diabetes, arterial hypertension, vasculopathy, ischemic etiology, NYHA functional class III-IV, eGFR, Hemoglobin, NT-ProBNP, LDL-P and treatment with ACEi/ARB, Betablockers, statins and ICD.

Model 2 Adjusted for Model 1 plus glycoprotein (Gly)-A, Gly-B and Gly-F.

*Other independent predictors of the outcomes in these models besides HDL-Sz or HDL-C/P were age, ischaemic etiology and NT-proBNP.