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. 2021 Feb 4;11:3049. doi: 10.1038/s41598-021-82614-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Evaluation of the toxicity or allergenicity of BEAP formulation. (A) Cytokine levels in the serum of BCG/BEAP immunized adult animal on D0 and at 2 months post immunization, (B) The granulocytes and WBC count in the control and post immunized infants. (C) Levels of liver secreted enzymes aspartate aminotransferase (AST), alanine aminotransferase (ALT) alkaline phosphatase (ALP) and cholesterol in the control and BCG/BEAP immunized infants at different time points. Dots indicate data points and bars are median with 95% confidence interval. Graphs were plotted using GraphPad Prism version-7 program (https://www.graphpad.com/).